Leukemia
Herausgeber
Nature Publishing Group
International Standard Serial Number (ISSN )
0887-6924
ISSN gedruckt
0887-6924
-
2025
DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes
2025 Dual STAT3/STAT5 inhibition as a novel treatment strategy in T-prolymphocytic leukemia
2024 Clonal medicine targeting DNA damage response eradicates leukemia
2023 Engraftment in NSGSCF mice correlates with the WHO category and prognosis in systemic mastocytosis.
2022 Refined diagnostic criteria for bone marrow mastocytosis: a proposal of the European competence network on mastocytosis
2021 Characterization of p190-Bcr-Abl chronic myeloid leukemia reveals specific signaling pathways and therapeutic targets
2021 Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness.
2021 Identification of gene targets of mutant C/EBPα reveals a critical role for MSI2 in CEBPA-mutated AML.
2021 Phenotypic characterization of leukemia-initiating stem cells in chronic myelomonocytic leukemia
2021 STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation
2019 CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex
2019 Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.
2019 Identification of a leukemia-initiating stem cell in human mast cell leukemia
2019 STAT5BN642H drives transformation of NKT cells: a novel mouse model for CD56+ T-LGL leukemia.
2019 The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis.
2019 Twins with different personalities: STAT5B-but not STAT5A-has a key role in BCR/ABL-induced leukemia
2018 Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells
2018 Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer
2018 Pharmacologic inhibition of STAT5 in acute myeloid leukemia
2018 The AP-1-BATF and-BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma
2017 A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation
2017 Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia.
2017 Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site
2017 O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies
2017 Proposed diagnostic criteria and classification of basophilic leukemias and related disorders.
2016 NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells
2016 Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth.
2016 The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.
2015 Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia.
2015 Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia.
2015 MARIMO cells harbor a CALR mutation but are not dependent on JAK2/STAT5 signaling.
2014 Acceleration of Bcr-Abl+ leukemia induced by deletion of JAK2.
2014 PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis.
2010 Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin.
2005 Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2.
-
Grebien, Florian
2018 -
Kenner, Lukas
2014
-
2025
DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes
2025 Dual STAT3/STAT5 inhibition as a novel treatment strategy in T-prolymphocytic leukemia
2024 Clonal medicine targeting DNA damage response eradicates leukemia
2023 Engraftment in NSGSCF mice correlates with the WHO category and prognosis in systemic mastocytosis.
2022 Refined diagnostic criteria for bone marrow mastocytosis: a proposal of the European competence network on mastocytosis
2021 Characterization of p190-Bcr-Abl chronic myeloid leukemia reveals specific signaling pathways and therapeutic targets
2021 Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness.
2021 Identification of gene targets of mutant C/EBPα reveals a critical role for MSI2 in CEBPA-mutated AML.
2021 Phenotypic characterization of leukemia-initiating stem cells in chronic myelomonocytic leukemia
2021 STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation
2019 CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex
2019 Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.
2019 Identification of a leukemia-initiating stem cell in human mast cell leukemia
2019 STAT5BN642H drives transformation of NKT cells: a novel mouse model for CD56+ T-LGL leukemia.
2019 The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis.
2019 Twins with different personalities: STAT5B-but not STAT5A-has a key role in BCR/ABL-induced leukemia
2018 Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells
2018 Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer
2018 Pharmacologic inhibition of STAT5 in acute myeloid leukemia
2018 The AP-1-BATF and-BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma
2017 A novel signalling screen demonstrates that CALR mutations activate essential MAPK signalling and facilitate megakaryocyte differentiation
2017 Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia.
2017 Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site
2017 O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies
2017 Proposed diagnostic criteria and classification of basophilic leukemias and related disorders.
2016 NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells
2016 Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth.
2016 The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models.
2015 Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia.
2015 Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia.
2015 MARIMO cells harbor a CALR mutation but are not dependent on JAK2/STAT5 signaling.
2014 Acceleration of Bcr-Abl+ leukemia induced by deletion of JAK2.
2014 PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis.
2010 Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin.
2005 Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2.
-
Grebien, Florian
2018 -
Kenner, Lukas
2014