Editorial overview: Viral zoonosis

Zoonotic spillover across species barriers continues to constitute a major threat and challenge to global health despite advances in surveillance, vaccine availability, and public risk awareness. In the last decade, wellknown examples include the Ebola epidemic in West Africa 2013-2016, the SARS-CoV-2 pandemic starting in 2019, and the widespread spread of Mpox outbreaks since 2022. The recent detection of Bundibugyo ebolavirus transmission in Central Africa illustrates that virus persistence in geographically remote, politically unstable, and economically disadvantaged areas may have a considerable impact on the vulnerability of human populations, particularly with low household incomes. Within this context, the articles summarized here review the latest findings concerning species barriers, pathogenesis, and the development of therapeutic countermeasures across diverse viral taxa.

Université de Lyon