Overexpression of human PHEX under the human beta-actin promoter does not fully rescue the Hyp mouse phenotype.

Autor:in

Erben, Reinhold G; Mayer, Dagmar; Weber, Karin; Jonsson, Kenneth; Jüppner, Harald; Lanske, Beate;

Schlagwörter

Actins/genetics*; Animals; Bone Density/genetics; Humans; Hypophosphatemia/genetics*; Hypophosphatemia/metabolism; Kidney/physiology; Mice; Mice, Transgenic; PHEX Phosphate Regulating Neutral Endopeptidase; Phenotype; Phosphates/blood; Phosphates/metabolism; Promoter Regions, Genetic/genetics; Proteins/analysis; Proteins/genetics*; Proteins/metabolism; Tissue Distribution; Transcriptional Activation; Transgenes;

ISSN/eISSN

0884-0431 -

WoS ID

WOS:000230134100008