Zeitschriftenaufsatz | 2021 Open Access

COVID-19 pandemic and allergen immunotherapy-an EAACI survey

Autor:in
Pfaar, Oliver; Agache, Ioana; Bonini, Matteo; Brough, Helen A.; Chivato, Tomas; Del Giacco, S.; Gawlik, Radoslaw; Akkor, Asli; Hoffmann-Sommergruber, Karin; Jutel, M.; Klimek, Ludger; Knol, Edward; Lauerma, Antti; Ollert, Markus W.; O'Mahony, Liam; Mortz, Charlotte G.; Palomares, Oscar; Riggioni, Carmen; Schwarze, Jürgen; Skypala, Isabel; Torres, Maria; Untersmayr, Eva; Walusiak-Skorupa, Jolanta; Chaker, Adam; Giovannini, Mattia; Heffler, Enrico; Jensen-Jarolim, Erika; Quecchia, Cristina; Sandoval-Ruballos, Monica; Sahiner, Umit; Tomic-Spiric, Vesna; Alvaro-Lozano, Montserrat
Publikationen als Autor:in / Herausgeber:in der Vetmeduni
Jensen-Jarolim, Erika
Journal
Allergy
Schlagwörter
allergen immunotherapy (AIT); COVID-19; pandemic; SARS-CoV-2; survey
Dokumenten­typ
Originalarbeit
CC Lizenz
CC-BY-NC
Open Access Type
Hybrid
ISSN/eISSN
0105-4538 - 1398-9995
DOI
Öffnen URL 10.1111/all.14793
WoS ID
Öffnen URL WOS:000688273400001
PubMed ID
Öffnen URL MEDLINE:33655519

Weitere Details

Band
76
Startseite
3504
Letzte Seite
3516
Nummer
11
Seiten­anzahl
13
Background As in many fields of medical care, the coronavirus disease 2019 (COVID-19) resulted in an increased uncertainty regarding the safety of allergen immunotherapy (AIT). Therefore, the European Academy of Allergy and Clinical Immunology (EAACI) aimed to analyze the situation in different countries and to systematically collect all information available regarding tolerability and possible amendments in daily practice of sublingual AIT (SLIT), subcutaneous AIT (SCIT) for inhalant allergies and venom AIT. Methods Under the framework of the EAACI, a panel of experts in the field of AIT coordinated by the Immunotherapy Interest Group set-up a web-based retrospective survey (SurveyMonkey(R)) including 27 standardized questions on practical and safety aspects on AIT in worldwide clinical routine. Results 417 respondents providing AIT to their patients in daily routine answered the survey. For patients (without any current symptoms to suspect COVID-19), 60% of the respondents informed of not having initiated SCIT (40% venom AIT, 35% SLIT) whereas for the maintenance phase of AIT, SCIT was performed by 75% of the respondents (74% venom AIT, 89% SLIT). No tolerability concern arises from this preliminary analysis. 16 physicians reported having performed AIT despite (early) symptoms of COVID-19 and/or a positive test result for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Conclusions This first international retrospective survey in atopic diseases investigated practical aspects and tolerability of AIT during the COVID-19 pandemic and gave no concerns regarding reduced tolerability under real-life circumstances. However, the data indicate an undertreatment of AIT, which may be temporary, but could have a long-lasting negative impact on the clinical care of allergic patients.

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