Supraagonistic, bispecific single-chain antibody purified from the serum of cloned, transgenic cows induces T-cell-mediated killing of glioblastoma cells in vitro and in vivo.

Autor:in

Grosse-Hovest, Ludger; Wick, Wolfgang; Minoia, Rosa; Weller, Michael; Rammensee, Hans-Georg; Brem, Gottfried; Jung, Gundram;

Schlagwörter

Animals; Animals, Genetically Modified/immunology*; Antibodies, Bispecific/blood*; Antigens, CD28/immunology*; Antigens, Neoplasm/immunology*; Cattle; Cell Division/immunology; Glioblastoma/immunology*; Glioblastoma/pathology; Humans; Killer Cells, Natural/immunology*; Kinetics; Lymphocyte Activation/immunology; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Proteoglycans/immunology*; T-Lymphocytes/immunology;

ISSN/eISSN

0020-7136 -

WoS ID

WOS:000233384900026