Zeitschriftenaufsatz | 2021 Open Access

Hydrogen Deuterium Exchange Mass Spectrometry identifies the dominant paratope in CD20 antigen binding to the NCD1.2 monoclonal antibody.

Autor:in

Uhrik, Lukas; Hernychova, Lenka; Muller, Petr; Kalathiya, Umesh; Lisowska, Malgorzata M; Kocikowski, Mikolaj; Parys, Maciej; Faktor, Jakub; Nekulova, Marta; Nortcliffe, Chris; Zatloukalova, Pavlina; Ruetgen, Barbara; Fahraeus, Robin; Ball, Kathryn L; Argyle, David J; Vojtesek, Borivoj; Hupp, Ted R

Publikationen als Autor:in / Herausgeber:in der Vetmeduni

Rütgen, Barbara

Journal

Biochemical Journal

Schlagwörter

Amino Acid Sequence; Animals; Antibodies, Monoclonalchemistrygenetics; Antigens, CD20immunology; Binding Sites, Antibody; Cell Line, Tumor; Chromatography, Liquid; Dogs; Humans; Hydrogen Deuterium Exchange-Mass Spectrometry; Immunoglobulin Gchemistry; Immunoglobulin Heavy Chainsgeneticsmetabolism; Immunoglobulin Light Chainsgeneticsmetabolism; Kinetics; Peptide Library; Recombinant Fusion Proteins; Tandem Mass Spectrometry

Dokumententyp

Originalarbeit

CC Lizenz

CCBY

Open Access Type

Hybrid

ISSN/eISSN

0264-6021 - 1470-8728

DOI

10.1042/BCJ20200674

WoS ID

WOS:000616136700002

PubMed ID

33284343