Accumulation of mutant neuroserpin precedes development of clinical symptoms in familial encephalopathy with neuroserpin inclusion bodies.

Autor:in

Galliciotti, Giovanna; Glatzel, Markus; Kinter, Jochen; Kozlov, Serguei V; Cinelli, Paolo; Rülicke, Thomas; Sonderegger, Peter;

Schlagwörter

Animals; Blotting, Western; Brain Diseases/genetics; Brain Diseases/metabolism; Brain Diseases/pathology*; Endoplasmic Reticulum, Rough/metabolism; Endoplasmic Reticulum, Rough/ultrastructure; Female; Humans; Inclusion Bodies/metabolism; Inclusion Bodies/pathology*; Inclusion Bodies/ultrastructure; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Transgenic; Microscopy, Electron; Mutant Proteins/metabolism*; Mutation; Neurons/metabolism; Neurons/pathology; Neurons/ultrastructure; Neuropeptides/genetics; Neuropeptides/metabolism*; Serpins/genetics; Serpins/metabolism*;

ISSN/eISSN

0002-9440 -

WoS ID

WOS:000245233000017