Zeitschriftenaufsatz | 2001 Open Access

Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression.

Autor:in

Kovarik, P; Mangold, M; Ramsauer, K; Heidari, H; Steinborn, R; Zotter, A; Levy, D E; Müller, M; Decker, T;

Publikationen als Autor:in / Herausgeber:in der Vetmeduni

Müller, Mathias; Steinborn, Ralf

Journal

EMBO Journal

Schlagwörter

3T3 Cells; Animals; DNA-Binding Proteins/deficiency; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism*; Gene Expression Regulation*/drug effects; Gene Expression Regulation*/radiation effects; Interferon-gamma/pharmacology; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases/metabolism; Phosphorylation; Polymerase Chain Reaction; Promoter Regions, Genetic/drug effects; Recombinant Proteins/metabolism; STAT1 Transcription Factor; Serine*; Signal Transduction/physiology*; Trans-Activators/deficiency; Trans-Activators/genetics; Trans-Activators/metabolism*; Transfection; Ultraviolet Rays; p38 Mitogen-Activated Protein Kinases; src Homology Domains;

Dokumententyp

Originalarbeit

ISSN/eISSN

0261-4189 -

DOI

10.1093/emboj/20.1.91

WoS ID

WOS:000166555700011

PubMed ID

11226159