Zeitschriftenaufsatz | 2008 Open Access

A novel endotoxin-induced pathway: upregulation of heme oxygenase 1, accumulation of free iron, and free iron-mediated mitochondrial dysfunction.

Autor:in

Duvigneau, J Catharina; Piskernik, Christina; Haindl, Susanne; Kloesch, Burkhard; Hartl, Romana T; Hüttemann, Maik; Lee, Icksoo; Ebel, Thomas; Moldzio, Rudolf; Gemeiner, Manfred; Redl, Heinz; Kozlov, Andrey V;

Publikationen als Autor:in / Herausgeber:in der Vetmeduni

Moldzio, Rudolf; Duvigneau, Catharina

Journal

Laboratory Investigation

Schlagwörter

Adenosine Triphosphate/metabolism; Animals; Endotoxins/pharmacology*; Gene Expression Profiling; Heme Oxygenase (Decyclizing)/metabolism*; Iron/metabolism*; Iron/pharmacology; Lipopolysaccharides/toxicity; Male; Mitochondria, Liver/drug effects*; Mitochondria, Liver/metabolism; Mitochondria, Liver/physiology; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species/metabolism; Up-Regulation/drug effects*;

Dokumententyp

Originalarbeit

ISSN/eISSN

0023-6837 -

DOI

10.1038/labinvest.3700691

WoS ID

WOS:000251820600007

PubMed ID

17982471