1alpha-hydroxyvitamin D2 is less toxic but not bone selective relative to 1alpha-hydroxyvitamin D3 in ovariectomized rats.

Autor:in

Weber, K; Goldberg, M; Stangassinger, M; Erben, R G;

Schlagwörter

Animals; Biotransformation; Bone Density/drug effects*; Bone and Bones/drug effects; Bone and Bones/metabolism; Calcinosis/chemically induced; Calcium/metabolism; Creatinine/metabolism; Ergocalciferols/pharmacokinetics; Ergocalciferols/pharmacology; Ergocalciferols/therapeutic use; Ergocalciferols/toxicity*; Female; Hydroxycholecalciferols/pharmacology; Hydroxycholecalciferols/therapeutic use; Hydroxycholecalciferols/toxicity*; Kidney Diseases/chemically induced; Lumbar Vertebrae/drug effects; Lumbar Vertebrae/ultrastructure; Organ Specificity; Osteocalcin/blood; Osteoporosis/drug therapy; Osteoporosis/metabolism*; Ovariectomy; Phosphorus/metabolism; Prodrugs/pharmacology; Prodrugs/toxicity*; Rats; Rats, Inbred F344; Tibia/drug effects; Tibia/ultrastructure; Urea/blood; Weight Gain;

ISSN/eISSN

0884-0431 -

WoS ID

WOS:000167610000005