Overexpression of RPGR leads to male infertility in mice due to defects in flagellar assembly.

Autor:in

Brunner, Sandra; Colman, Dvora; Travis, Alexander J; Luhmann, Ulrich F O; Shi, Wei; Feil, Silke; Imsand, Coni; Nelson, Jacquelyn; Grimm, Christian; Rülicke, Thomas; Fundele, Reinald; Neidhardt, John; Berger, Wolfgang;

Schlagwörter

Animals; Biological Transport/genetics; Carrier Proteins/genetics*; Carrier Proteins/metabolism; Carrier Proteins/physiology; Eye Proteins/genetics*; Eye Proteins/metabolism; Eye Proteins/physiology; Gene Dosage/physiology; Infertility, Male/genetics*; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Sperm Tail/metabolism*; Sperm Tail/physiology; Sperm Tail/ultrastructure; Spermatogenesis/genetics*; Spermatozoa/abnormalities*; Testis/cytology; Up-Regulation/physiology;

ISSN/eISSN

0006-3363 -

WoS ID

WOS:000259305300004