NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase.

Autor:in

Habjan, Matthias; Pichlmair, Andreas; Elliott, Richard M; Overby, Anna K; Glatter, Timo; Gstaiger, Matthias; Superti-Furga, Giulio; Unger, Hermann; Weber, Friedemann;

Schlagwörter

Animals; Antiviral Agents/pharmacology; Cells, Cultured; Cercopithecus aethiops; Humans; Interferons/pharmacology; Mice; Mice, Knockout; Phenotype; Proteasome Endopeptidase Complex/metabolism; RNA, Double-Stranded; Rift Valley fever virus/drug effects; Rift Valley fever virus/genetics; Rift Valley fever virus/metabolism*; Substrate Specificity; Viral Nonstructural Proteins/genetics; Viral Nonstructural Proteins/metabolism*; Virus Replication/drug effects; eIF-2 Kinase/deficiency; eIF-2 Kinase/genetics; eIF-2 Kinase/metabolism*;

ISSN/eISSN

0022-538X -

WoS ID

WOS:000265041600036

Titel des Sammelwerks

JOURNAL OF VIROLOGY;