Zeitschriftenaufsatz
|
2010
Polo-like kinase 1 (Plk1) as a novel drug target in chronic myeloid leukemia: overriding imatinib resistance with the Plk1 inhibitor BI 2536.
Autor:in
Gleixner, Karoline V; Ferenc, Veronika; Peter, Barbara; Gruze, Alexander; Meyer, Renata A; Hadzijusufovic, Emir; Cerny-Reiterer, Sabine; Mayerhofer, Matthias; Pickl, Winfried F; Sillaber, Christian; Valent, Peter;
Publikationen als Autor:in / Herausgeber:in der Vetmeduni
Journal
Schlagwörter
Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Benzamides; Cell Cycle Proteins/antagonists & inhibitors*; Cell Cycle Proteins/genetics; Cell Cycle Proteins/physiology; Drug Delivery Systems/methods; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm/drug effects*; Female; Fusion Proteins, bcr-abl/genetics; Fusion Proteins, bcr-abl/physiology; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/blood; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy*; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics; Male; Middle Aged; Piperazines/therapeutic use*; Protein Kinase Inhibitors/therapeutic use; Protein-Serine-Threonine Kinases/antagonists & inhibitors*; Protein-Serine-Threonine Kinases/genetics; Protein-Serine-Threonine Kinases/physiology; Proto-Oncogene Proteins/antagonists & inhibitors*; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins/physiology; Pteridines/administration & dosage; Pteridines/therapeutic use*; Pyrimidines/therapeutic use*;
Dokumententyp
Originalarbeit
ISSN/eISSN
0008-5472 -
10.1158/0008-5472.CAN-09-2181
WoS ID
PubMed ID
Titel des Sammelwerks
CANCER RESEARCH;