Zeitschriftenaufsatz
|
2011
KIT-D816V-independent oncogenic signaling in neoplastic cells in systemic mastocytosis: role of Lyn and Btk activation and disruption by dasatinib and bosutinib.
Autor:in
Gleixner, Karoline V; Mayerhofer, Matthias; Cerny-Reiterer, Sabine; Hörmann, Gregor; Rix, Uwe; Bennett, Keiryn L; Hadzijusufovic, Emir; Meyer, Renata A; Pickl, Winfried F; Gotlib, Jason; Horny, Hans-Peter; Reiter, Andreas; Mitterbauer-Hohendanner, Gerlinde; Superti-Furga, Giulio; Valent, Peter;
Publikationen als Autor:in / Herausgeber:in der Vetmeduni
Journal
Schlagwörter
Aniline Compounds/pharmacology*; Cell Line, Tumor; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Mast Cells/metabolism; Mast Cells/pathology; Mastocytosis, Systemic/drug therapy*; Mastocytosis, Systemic/genetics; Mastocytosis, Systemic/metabolism; Mutation; Nitriles/pharmacology*; Phosphorylation/drug effects; Protein Kinase Inhibitors/pharmacology*; Protein-Tyrosine Kinases/genetics; Protein-Tyrosine Kinases/metabolism*; Proto-Oncogene Proteins c-kit/genetics*; Proto-Oncogene Proteins c-kit/metabolism; Pyrimidines/pharmacology*; Quinolines/pharmacology*; Signal Transduction/drug effects; Staurosporine/analogs & derivatives; Staurosporine/pharmacology; Thiazoles/pharmacology*; Tumor Cells, Cultured; src-Family Kinases/genetics; src-Family Kinases/metabolism*;
Dokumententyp
Originalarbeit
ISSN/eISSN
0006-4971 -
10.1182/blood-2010-06-289959
WoS ID
PubMed ID
Titel des Sammelwerks
BLOOD;