Zeitschriftenaufsatz | 2011 Open Access

High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia.

Autor:in

Warsch, Wolfgang; Kollmann, Karoline; Eckelhart, Eva; Fajmann, Sabine; Cerny-Reiterer, Sabine; Hölbl, Andrea; Gleixner, Karoline V; Dworzak, Michael; Mayerhofer, Matthias; Hoermann, Gregor; Herrmann, Harald; Sillaber, Christian; Egger, Gerda; Valent, Peter; Moriggl, Richard; Sexl, Veronika;

Publikationen als Autor:in / Herausgeber:in der Vetmeduni

Sexl, Veronika; Kollmann, Karoline

Journal

Blood

Schlagwörter

Animals; Antineoplastic Agents/therapeutic use; Benzamides; Cells, Cultured; Disease Progression; Drug Resistance, Neoplasm/genetics*; Gene Expression Regulation, Neoplastic/physiology; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/diagnosis; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy*; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/genetics*; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Piperazines/therapeutic use*; Prognosis; Pyrimidines/therapeutic use*; STAT5 Transcription Factor/genetics; STAT5 Transcription Factor/physiology*; Treatment Failure; Up-Regulation/genetics; Up-Regulation/physiology; Xenograft Model Antitumor Assays;

Dokumententyp

Originalarbeit

ISSN/eISSN

0006-4971 -

DOI

10.1182/blood-2009-10-248211

WoS ID

WOS:000288848500024

PubMed ID

21220747

Projekt

Flow cytometric signal typing for therapy response

Titel des Sammelwerks

BLOOD;