Zeitschriftenaufsatz | 2010

KIT polymorphisms and mutations determine responses of neoplastic mast cells to bafetinib (INNO-406).

Autor:in
Peter, Barbara; Hadzijusufovic, Emir; Blatt, Katharina; Gleixner, Karoline V; Pickl, Winfried F; Thaiwong, Tuddow; Yuzbasiyan-Gurkan, Vilma; Willmann, Michael; Valent, Peter;
Publikationen als Autor:in / Herausgeber:in der Vetmeduni
Schlagwörter
Amino Acid Substitution; Animals; Dogs; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm*; Drug Screening Assays, Antitumor; Exons/genetics; Gene Expression Regulation, Enzymologic/drug effects; Gene Expression Regulation, Enzymologic/genetics; Gene Expression Regulation, Neoplastic/drug effects; Gene Expression Regulation, Neoplastic/genetics; Humans; Mast Cells*/enzymology; Mast Cells*/pathology; Mastocytosis, Systemic*/drug therapy; Mastocytosis, Systemic*/enzymology; Mastocytosis, Systemic*/genetics; Mastocytosis, Systemic*/pathology; Mutation, Missense*; Phosphorylation/drug effects; Phosphorylation/genetics; Polymorphism, Genetic*; Protein Kinase Inhibitors/pharmacology*; Proto-Oncogene Proteins c-kit/antagonists & inhibitors*; Proto-Oncogene Proteins c-kit/genetics; Proto-Oncogene Proteins c-kit/metabolism*; Pyrimidines/pharmacology*; Species Specificity;
Dokumententyp
Originalarbeit
ISSN/eISSN
0301-472X -
PubMed ID
Titel des Sammelwerks
EXPERIMENTAL HEMATOLOGY;

Weitere Details

Band
38
Startseite
782
letzte Seite
791
Nummer
9