Zeitschriftenaufsatz
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2011
Polo-like kinase-1 as a novel target in neoplastic mast cells: demonstration of growth-inhibitory effects of small interfering RNA and the Polo-like kinase-1 targeting drug BI 2536.
Autor:in
Peter, Barbara; Gleixner, Karoline V; Cerny-Reiterer, Sabine; Herrmann, Harald; Winter, Viviane; Hadzijusufovic, Emir; Ferenc, Veronika; Schuch, Karina; Mirkina, Irina; Horny, Hans-Peter; Pickl, Winfried F; Müllauer, Leonhard; Willmann, Michael; Valent, Peter;
Publikationen als Autor:in / Herausgeber:in der Vetmeduni
Schlagwörter
Animals; Apoptosis/drug effects; Cell Cycle/drug effects; Cell Cycle Proteins/antagonists & inhibitors; Cell Cycle Proteins/genetics; Cell Cycle Proteins/metabolism*; Cell Line, Tumor; Cell Proliferation/drug effects; Dose-Response Relationship, Drug; Flow Cytometry; HL-60 Cells; Humans; Immunohistochemistry; K562 Cells; Mast Cells/drug effects; Mast Cells/metabolism*; Mast Cells/pathology; Mastocytosis, Systemic/genetics; Mastocytosis, Systemic/metabolism*; Mastocytosis, Systemic/pathology; Phosphorylation; Protein-Serine-Threonine Kinases/antagonists & inhibitors; Protein-Serine-Threonine Kinases/genetics; Protein-Serine-Threonine Kinases/metabolism*; Proto-Oncogene Proteins/antagonists & inhibitors; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins/metabolism*; Pteridines/pharmacology; RNA Interference; Reverse Transcriptase Polymerase Chain Reaction; Thymidine/metabolism; Thymidine/pharmacokinetics; Tumor Cells, Cultured; U937 Cells;
Dokumententyp
Originalarbeit
ISSN/eISSN
0390-6078 -
10.3324/haematol.2010.031328
WoS ID
PubMed ID
Titel des Sammelwerks
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL;