5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand.

Publikationen als Autor:in / Herausgeber:in der Vetmeduni

Hadzijusufovic, Emir

Schlagwörter

Adult; Aged; Antigens, CD95/antagonists & inhibitors; Antigens, CD95/genetics; Antigens, CD95/metabolism*; Antimetabolites, Antineoplastic/pharmacology*; Apoptosis/drug effects*; Azacitidine/analogs & derivatives*; Azacitidine/pharmacology*; Base Sequence; Cell Line, Tumor/drug effects; CpG Islands; DNA Methylation/drug effects; DNA, Neoplasm/metabolism; Drug Synergism; Fas Ligand Protein/physiology; Female; Humans; Leukemia, Mast-Cell/pathology*; Male; Mast Cells/drug effects*; Mast Cells/pathology; Mastocytosis, Systemic/pathology*; Methylation/drug effects; Middle Aged; Molecular Sequence Data; Neoplasm Proteins/metabolism; Point Mutation; Promoter Regions, Genetic/genetics; Protein Processing, Post-Translational/drug effects*; Proto-Oncogene Proteins c-kit/genetics; RNA, Small Interfering/pharmacology;

ISSN/eISSN

0006-4971 -

WoS ID

WOS:000305284600021

Titel des Sammelwerks

BLOOD;