Zeitschriftenaufsatz | 2012 Open Access

TYK2 kinase activity is required for functional type I interferon responses in vivo.

Autor:in

Prchal-Murphy, Michaela; Semper, Christian; Lassnig, Caroline; Wallner, Barbara; Gausterer, Christian; Teppner-Klymiuk, Ingeborg; Kobolak, Julianna; Müller, Simone; Kolbe, Thomas; Karaghiosoff, Marina; Dinnyés, Andras; Rülicke, Thomas; Leitner, Nicole R; Strobl, Birgit; Müller, Mathias;

Publikationen als Autor:in / Herausgeber:in der Vetmeduni

Karaghiosoff, Marina; Müller, Mathias; Lassnig, Caroline; Prchal-Murphy, Michaela; Wallner, Barbara; Strobl, Birgit; Kolbe, Thomas

Journal

PLoS One

Schlagwörter

Adaptive Immunity/genetics; Amino Acid Sequence; Animals; Base Sequence; Enzyme Activation/genetics; Gene Order; Gene Targeting; Genetic Predisposition to Disease; Immunity, Innate/genetics; Interferon Type I/pharmacology*; Interferon-beta/immunology; Interferon-beta/pharmacology; Janus Kinases/metabolism; Mice; Mice, Knockout; Mutation; Organ Specificity/genetics; Protein Stability; STAT Transcription Factors/metabolism; Signal Transduction/drug effects; TYK2 Kinase/genetics; TYK2 Kinase/metabolism*; Transcriptional Activation/drug effects; Virus Diseases/genetics; Virus Diseases/immunology; Virus Diseases/metabolism;

Dokumententyp

Originalarbeit

ISSN/eISSN

1932-6203 -

DOI

10.1371/journal.pone.0039141

WoS ID

WOS:000305583300102

PubMed ID

22723949

Titel des Sammelwerks

PLOS ONE;