Zeitschriftenaufsatz | 2014

Tocopheramine succinate and tocopheryl succinate: mechanism of mitochondrial inhibition and superoxide radical production.

Autor:in

Gruber, Julia; Staniek, Katrin; Krewenka, Christopher; Moldzio, Rudolf; Patel, Anjan; Böhmdorfer, Stefan; Rosenau, Thomas; Gille, Lars;

Publikationen als Autor:in / Herausgeber:in der Vetmeduni

Staniek, Katrin; Moldzio, Rudolf; Gille, Lars

Journal

Bioorganic & Medicinal Chemistry

Schlagwörter

Antineoplastic Agents/chemistry; Antineoplastic Agents/metabolism; Antineoplastic Agents/pharmacology*; Cell Survival/drug effects; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Electron Transport Complex I/antagonists & inhibitors; Electron Transport Complex I/metabolism; Electron Transport Complex II/antagonists & inhibitors; Electron Transport Complex II/metabolism; Electron Transport Complex III/antagonists & inhibitors; Electron Transport Complex III/metabolism; Free Radicals/metabolism; HeLa Cells; Humans; Mitochondria/drug effects*; Mitochondria/metabolism; Molecular Structure; Structure-Activity Relationship; Submitochondrial Particles/drug effects; Submitochondrial Particles/metabolism; Succinates/chemistry; Succinates/metabolism; Succinates/pharmacology*; Superoxides/metabolism*; Tumor Cells, Cultured; Vitamin E/analogs & derivatives*; Vitamin E/chemistry; Vitamin E/metabolism; Vitamin E/pharmacology; alpha-Tocopherol/chemistry; alpha-Tocopherol/metabolism; alpha-Tocopherol/pharmacology*;

Dokumententyp

Originalarbeit

ISSN/eISSN

0968-0896 -

DOI

10.1016/j.bmc.2013.12.036

WoS ID

WOS:000329576400002

PubMed ID

24393721