Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier.

Autor:in

Pollak, Nina M; Schweiger, Martina; Jaeger, Doris; Kolb, Dagmar; Kumari, Manju; Schreiber, Renate; Kolleritsch, Stephanie; Markolin, Philipp; Grabner, Gernot F; Heier, Christoph; Zierler, Kathrin A; Rülicke, Thomas; Zimmermann, Robert; Lass, Achim; Zechner, Rudolf; Haemmerle, Guenter;

Schlagwörter

1-Acylglycerol-3-Phosphate O-Acyltransferase/genetics; 1-Acylglycerol-3-Phosphate O-Acyltransferase/metabolism; Animals; COS Cells; Cardiomyopathies/genetics; Cardiomyopathies/metabolism*; Energy Metabolism/genetics; Energy Metabolism/physiology; Immunoblotting; Intracellular Signaling Peptides and Proteins/genetics; Intracellular Signaling Peptides and Proteins/metabolism*; Lipase/genetics; Lipase/metabolism; Lipolysis/genetics; Lipolysis/physiology*; Mice; Mice, Transgenic; Muscle Proteins/genetics; Muscle Proteins/metabolism*; Myocardium/metabolism; Myocardium/pathology; Triglycerides/metabolism;

ISSN/eISSN

0022-2275 -

WoS ID

WOS:000316462600021