Postnatal establishment of allelic Gαs silencing as a plausible explanation for delayed onset of parathyroid hormone resistance owing to heterozygous Gαs disruption.

Autor:in

Turan, Serap; Fernandez-Rebollo, Eduardo; Aydin, Cumhur; Zoto, Teuta; Reyes, Monica; Bounoutas, George; Chen, Min; Weinstein, Lee S; Erben, Reinhold G; Marshansky, Vladimir; Bastepe, Murat;

Schlagwörter

Alleles*; Animals; Drug Resistance; Female; GTP-Binding Protein alpha Subunits, Gs/genetics*; GTP-Binding Protein alpha Subunits, Gs/metabolism; Gene Silencing*; Heterozygote*; Kidney Tubules, Proximal/metabolism; Male; Mice; Mutation; Parathyroid Hormone/therapeutic use*;

Open Access Type

Green

DOI

10.1002/jbmr.2070

PubMed ID

23956044