Zeitschriftenaufsatz
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2013
TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia.
Autor:in
Sanda, Takaomi; Tyner, Jeffrey W; Gutierrez, Alejandro; Ngo, Vu N; Glover, Jason; Chang, Bill H; Yost, Arla; Ma, Wenxue; Fleischman, Angela G; Zhou, Wenjun; Yang, Yandan; Kleppe, Maria; Ahn, Yebin; Tatarek, Jessica; Kelliher, Michelle A; Neuberg, Donna S; Levine, Ross L; Moriggl, Richard; Müller, Mathias; Gray, Nathanael S; Jamieson, Catriona H M; Weng, Andrew P; Staudt, Louis M; Druker, Brian J; Look, A Thomas;
Publikationen als Autor:in / Herausgeber:in der Vetmeduni
Journal
Schlagwörter
Animals; Antineoplastic Agents/pharmacology; Bone Marrow Cells; Cell Line; Cell Survival/drug effects; Cells, Cultured; Humans; Interleukin-10/metabolism; Janus Kinase 3/antagonists & inhibitors; Leukocytes, Mononuclear/drug effects; Leukocytes, Mononuclear/metabolism; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Piperidines/pharmacology; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism*; Protein Kinase Inhibitors/pharmacology; Proto-Oncogene Proteins c-bcl-2/metabolism*; Pyrimidines/pharmacology; Pyrroles/pharmacology; RNA Interference; STAT1 Transcription Factor/genetics; STAT1 Transcription Factor/metabolism*; Signal Transduction; TYK2 Kinase/antagonists & inhibitors; TYK2 Kinase/genetics; TYK2 Kinase/metabolism*; Tyrphostins/pharmacology;
Dokumententyp
Originalarbeit
ISSN/eISSN
2159-8274 -
10.1158/2159-8290.CD-12-0504
WoS ID
PubMed ID