Listeria monocytogenes modulates macrophage cytokine responses through STAT serine phosphorylation and the induction of suppressor of cytokine signaling 3.

Autor:in

Stoiber, D; Stockinger, S; Steinlein, P; Kovarik, J; Decker, T;

Schlagwörter

Animals; Cell Line; Cytokines/biosynthesis*; DNA-Binding Proteins/antagonists & inhibitors; DNA-Binding Proteins/metabolism*; DNA-Binding Proteins/physiology; Enzyme Activation/immunology; Gene Expression Regulation/immunology; Granulocyte-Macrophage Colony-Stimulating Factor/antagonists & inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology; I-kappa B Proteins/metabolism; Intracellular Fluid/immunology; Intracellular Fluid/metabolism; Intracellular Fluid/microbiology; Janus Kinase 1; Listeria monocytogenes/immunology*; Macrophages/enzymology; Macrophages/immunology*; Macrophages/metabolism*; Macrophages/microbiology; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases/metabolism; Peptides/secretion; Phosphorylation; Phosphotyrosine/antagonists & inhibitors; Phosphotyrosine/metabolism; Protein Biosynthesis*; Protein-Tyrosine Kinases/antagonists & inhibitors; Protein-Tyrosine Kinases/metabolism; Proteins/genetics; Proteins/physiology; Repressor Proteins*; STAT1 Transcription Factor; Serine/metabolism*; Signal Transduction/immunology*; Suppressor of Cytokine Signaling Proteins; Trans-Activators/antagonists & inhibitors; Trans-Activators/metabolism*; Trans-Activators/physiology; Transcription Factors*; p38 Mitogen-Activated Protein Kinases;

ISSN/eISSN

0022-1767 -

PubMed ID

11123325