Zeitschriftenaufsatz | 2014

Loss of STAT3 in murine NK cells enhances NK cell-dependent tumor surveillance.

Autor:in

Gotthardt, Dagmar; Putz, Eva M; Straka, Elisabeth; Kudweis, Petra; Biaggio, Mario; Poli, Valeria; Strobl, Birgit; Müller, Mathias; Sexl, Veronika;

Publikationen als Autor:in / Herausgeber:in der Vetmeduni

Müller, Mathias; Gotthardt-Pötsch, Dagmar; Strobl, Birgit; Sexl, Veronika

Journal

Blood

Schlagwörter

Animals; Antigens, Ly/metabolism; Cell Differentiation/drug effects; Cell Proliferation/drug effects; Cytokines/pharmacology; Disease Models, Animal; Granzymes/metabolism; Immunologic Surveillance*/drug effects; Integrases/metabolism; Interferon-gamma/biosynthesis; Interferon-gamma/genetics; Intestines/pathology; Killer Cells, Natural/cytology; Killer Cells, Natural/drug effects; Killer Cells, Natural/metabolism*; Kinetics; Melanoma, Experimental/pathology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Natural Cytotoxicity Triggering Receptor 1/metabolism; Neoplasms/immunology*; Neoplasms/metabolism*; Perforin/metabolism; Promoter Regions, Genetic/genetics; Protein Binding/drug effects; STAT3 Transcription Factor/metabolism*; Spleen/pathology;

Dokumententyp

Originalarbeit

ISSN/eISSN

0006-4971 -

DOI

10.1182/blood-2014-03-564450

WoS ID

WOS:000347454400015

PubMed ID

25185262

Projekt

Stat3 a und b dissecting the tumor-suppressing effects of stat3 in NK-cell surveilled tumors