Zeitschriftenaufsatz
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2017
Commensal or pathogen - a challenge to fulfil Koch's Postulates
Autor:in
Hess, Michael
Journal
Abstrakt
1. Infectious diseases have a large impact on poultry health and economics. Elucidating the pathogenesis of a certain disease is crucial to implement control strategies.2. Multiplication of a pathogen and its characterisation in vitro are basic requirements to perform experimental studies. However, passaging of the pathogen in vitro can influence the pathogenicity, a process targeted for live vaccine development, but limits the reproduction of clinical signs.3. Numerous factors can influence the outcome of experimental infections with some importance on the pathogen, application route and host as exemplarily outlined for Histomonas meleagridis, Gallibacterium anatis and fowl aviadenoviruses (FAdVs).4. In future, more comprehensive and detailed settings are needed to obtain as much information as possible from animal experiments. Processing of samples with modern diagnostic tools provides the option to closely monitor the host-pathogen interaction.
Schlagwörter
Adenoviridae Infectionshistoryveterinary; Animals; Aviadenovirusclassification; Chickens; England; Fowl adenovirus A; History, 19th Century; History, 20th Century; History, 21st Century; Host-Pathogen Interactions; Pasteurellaceaeclassification; Pasteurellaceae Infectionshistorymicrobiologyveterinary; Poultry Diseaseshistorymicrobiologyparasitology; Protozoan Infections, Animalhistoryparasitology; Symbiosis
Dokumententyp
Originalarbeit
CC Lizenz
CCBYNCND
Open Access Type
Hybrid
ISSN/eISSN
0007-1668 - 1466-1799
10.1080/00071668.2016.1245849
WoS ID
PubMed ID