Down-regulation of c-Cbl by morphine accounts for persistent ERK1/2 signaling in delta-opioid receptor-expressing HEK293 cells.

Autor:in

Eisinger, Daniela A; Ammer, Hermann;

Schlagwörter

Animals; Cell Line; Down-Regulation/drug effects*; Enzyme Activation; Etorphine/pharmacology; Humans; MAP Kinase Signaling System/drug effects*; Membrane Microdomains/metabolism; Mice; Mitogen-Activated Protein Kinase 1/metabolism*; Mitogen-Activated Protein Kinase 3/metabolism*; Morphine/pharmacology*; Narcotics/pharmacology; Protein-Tyrosine Kinases/metabolism; Proto-Oncogene Proteins c-cbl/metabolism*; RNA, Small Interfering/genetics; RNA, Small Interfering/metabolism; Receptor, Epidermal Growth Factor/metabolism; Receptors, Opioid, delta/metabolism*; src-Family Kinases;

ISSN/eISSN

0021-9258 -

WoS ID

WOS:000272439600037