Zeitschriftenaufsatz | 2019 Open Access

Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series

Autor:in

Fages, Antoine; Hanghoj, Kristian Ebbesen; Khan, Naveed; Gaunitz, Charleen; Seguin-Orlando, Andaine; Leonardi, Michela; Constantz, Christian; Gamba, Cristina; AL-Rasheid, Khaled; Albizuri, Silvia; Alfarhan, Ahmed; Allentoft, Morten E.; Alquraishi, Saleh; Anthony, David; Baimukhanov, Nurbol; Barrett, James H.; Bayarsaikhan, Jamsranjav; Benecke, Norbert; Bernáldez-Sánchez, Eloísa; Berrocal-Rangel, Luis; Biglari, Fereidoun; Boessenkool, Sanne; Boldgiv, Bazartseren; Brem, G.; Brown, Dorcas R.; Burger, Joachim; Crubézy, Eric; Daugnora, Linas; Davoudi, Hossein; Damgaard, Peter de Barros; de Chorro y de Villa-Ceballos, Maria de los Angeles; Deschler-Erb, Sabine; Detry, Cleia; Dill, Nadine; do Mar Oom, Maria; Dohr, Anna; Ellingvag, Sturla; Erdenebaatar, Diimaajav; Fathi, Homa; Felkel, S.; Fernández-Rodríguez, Carlos; García-Viñas, Esteban; Germonpré, Mietje; Granado, J.; Hallsson, Jon; Hemmer, Helmut; Hofreiter, Michael; Kasparov, A. K.; Khasanov, Mutalib; Khazaeli, Roya; Kosintsev, Pavel; Kristiansen, Kristian; Tabaldiev, Kubatbek; Kuderna, L. F. K.; Kuznetsov, Pavel; Laleh, Haeedeh; Leonard, Jennifer; Lhuillier, Johanna; Liesau, Corina; Logvin, Andrey; Lõugas, Lembi; Ludwig, Arne; Luis, Cristina; Arruda, Ana; Marques-Bonet, Tomas; M. Silva, Raquel; Merts, Viktor; Mijiddorj, Enkhbayar; Miller, Bryan; Monchalov, Oleg; Mohaseb, Azadeh F.; Muñiz, Arturo; Nieto Espinet, Ariadna; Nistelberger, Heidi M.; Onar, Vedat; Palsdottir, Albina; Pitulko, Vladimir; Pitskhelauri, Konstantin; Pruvost, Melanie; Sikanjic, Petra Rajic; Papesa, Anita Rapan; Рослякова, Наталья; Sardari, Alireza; Sauer, Eberhard; Schafberg, Renate; Scheu, Amelie; Schibler, Jorg M.; Schlumbaum, Angela; Serrand, Nathalie; Serres-Armero, Aitor; Shapiro, B.; Seno, Shiva Sheikhi; Irina, Shevnina; Shidrang, Sonia; Southon, John; Star, Bastiaan; Sykes, Naomi; Taheri, Kamal; Taylor, William; Teegen, Wolf-Rüdiger; Vukicevic, Tajana Trbojevic; Trixl, Simon; Tumen, D.; Undrakhbold, Sainbileg; Usmanova, Emma R.; Vahdati, Ali; Valenzuela-Lamas, Silvia; Viegas, Catarina; Wallner, Barbara; Weinstock, J.; Zaibert, Victor F.; Clavel, Benoit; Lepetz, Sebastien; Mashkour, Marjan; Helgason, Agnar; Stefansson, Kari; eb, equipe; Willerslev, Eske; Outram, Alan; Librado, Pablo; ORLANDO, Ludovic

Publikationen als Autor:in / Herausgeber:in der Vetmeduni

Wallner, Barbara

Journal

Cell

Schlagwörter

Animals; Asia; Biological Evolution; Breedinghistory; DNA, Ancientanalysis; Domestication; Equidaegenetics; Europe; Female; Genetic Variationgenetics; Genomegenetics; History, Ancient; Horsesgenetics; Male; Phylogeny

Dokumententyp

Originalarbeit

CC Lizenz

CC-BY-NC-ND

Open Access Type

Hybrid

ISSN/eISSN

0092-8674 - 1097-4172

DOI

10.1016/j.cell.2019.03.049

WoS ID

WOS:000469415100010

PubMed ID

MEDLINE:31056281

Weitere Details

Band

177

Startseite

1419

Letzte Seite

Nummer

Seitenanzahl

Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (>= 1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modem legacy of past equestrian civilisations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse lineages increased following the Islamic conquests in Europe and Asia. Multiple alleles associated with elite-racing, including at the MSTN "speed gene," only rose in popularity within the last millennium. Finally, the development of modem breeding impacted genetic diversity more dramatically than the previous millennia of human management. Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (≥1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modern legacy of past equestrian civilizations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse lineages increased following the Islamic conquests in Europe and Asia. Multiple alleles associated with elite-racing, including at the MSTN "speed gene," only rose in popularity within the last millennium. Finally, the development of modern breeding impacted genetic diversity more dramatically than the previous millennia of human management.Copyright © 2019 The Author(s). Published by Elsevier Inc. All rights reserved.