The unfolded protein response impacts melanoma progression by enhancing FGF expression and can be antagonized by a chemical chaperone.

Autor:in

Eigner, Karin; Filik, Yüksel; Mark, Florian; Schütz, Birgit; Klambauer, Günter; Moriggl, Richard; Hengstschläger, Markus; Stangl, Herbert; Mikula, Mario; Röhrl, Clemens

Schlagwörter

Animals; Antineoplastic Agentspharmacology; Biomarkers, Tumormetabolism; Butylaminespharmacology; Cell Line, Tumor; Cell Movementphysiology; Cell Survivaldrug effectsphysiology; Disease Progression; Endoplasmic Reticulum Stressphysiology; Fibroblast Growth Factorsmetabolism; Gene Expression Regulation, Neoplasticdrug effectsphysiology; Humans; Melanocytesdrug effectsmetabolism; Melanomadrug therapygeneticsmetabolism; Mice; Mutation; Neoplasm Transplantation; Proto-Oncogene Proteins B-rafgeneticsmetabolism; Unfolded Protein Responsedrug effects

CC Lizenz

CCBY

ISSN/eISSN

2045-2322 -

WoS ID

WOS:000417796000018