Zeitschriftenaufsatz
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2018
The 3Rs Concept: Time to Change How We Evaluate the Efficacy of Anthelmintics in Companion Animals
Autor:in
Traversa, Donato; Joachim, Anja
Publikationen als Autor:in / Herausgeber:in der Vetmeduni
Journal
Abstrakt
Experimental infections are required by current guidelines for investigating the efficacy of anthelmintics in dogs and cats. Recently, alternatives to experimental infections and the sacrificing of research dogs and cats have been evaluated, and novel conceptual investigations and methods of examination have been explored. Several of these approaches could potentially be used in efficacy studies for anthelmintics in dogs and cats. Here, we provide food for thought towards using new tools for evaluating the efficacy of anthelmintics in companion animals, for promoting the value of field trials, and for updating the existing guidelines for the efficacy testing of anthelmintics in dogs and cats.
Schlagwörter
Animals; Anthelminticsadministration & dosagestandards; Cat Diseasesdrug therapyprevention & control; Cats; Dog Diseasesdrug therapyprevention & control; Dogs; Drug Evaluationstandardsveterinary; Helminthiasis, Animaldrug therapyprevention & control; Petsparasitology
Dokumententyp
Übersichtsarbeit
ISSN/eISSN
1471-4922 - 1471-5007
10.1016/j.pt.2017.09.002
WoS ID
PubMed ID