Zeitschriftenaufsatz
|
2012
Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.
Autor:in
Winter, Georg E; Rix, Uwe; Carlson, Scott M; Gleixner, Karoline V; Grebien, Florian; Gridling, Manuela; Müller, André C; Breitwieser, Florian P; Bilban, Martin; Colinge, Jacques; Valent, Peter; Bennett, Keiryn L; White, Forest M; Superti-Furga, Giulio;
Publikationen als Autor:in / Herausgeber:in der Vetmeduni
Journal
Schlagwörter
Aniline Compounds/pharmacology*; Animals; Antineoplastic Combined Chemotherapy Protocols/pharmacology*; Apoptosis/drug effects; Benzamides/pharmacology*; Cell Line, Tumor; Cell Survival/drug effects; Dose-Response Relationship, Drug; Down-Regulation/drug effects; Drug Resistance, Neoplasm/drug effects*; Drug Synergism; Fusion Proteins, bcr-abl/antagonists & inhibitors; Fusion Proteins, bcr-abl/genetics; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy*; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/metabolism; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/pathology; Mice; Nitriles/pharmacology*; Piperazines/pharmacology*; Protein Kinase Inhibitors/pharmacology*; Proteomics; Proto-Oncogene Proteins c-myc/antagonists & inhibitors; Proto-Oncogene Proteins c-myc/metabolism; Pyrazoles/pharmacology*; Pyrimidines/pharmacology*; Quinolines/pharmacology*; Structure-Activity Relationship; Systems Biology;
Dokumententyp
Originalarbeit
ISSN/eISSN
1552-4450 -
10.1038/nchembio.1085
WoS ID
PubMed ID