Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis.

Autor:in

Manils, Joan; Gómez, Diana; Salla-Martret, Mercè; Fischer, Heinz; Fye, Jason M; Marzo, Elena; Marruecos, Laura; Serrano, Inma; Salgado, Rocío; Rodrigo, Juan P; Garcia-Pedrero, Juana M; Serafin, Anna M; Cañas, Xavier; Benito, Carmen; Toll, Agustí; Forcales, Sònia-Vanina; Perrino, Fred W; Eckhart, Leopold; Soler, Concepció;

Schlagwörter

Animals; Carcinoma, Squamous Cell/enzymology*; Carcinoma, Squamous Cell/etiology; Carcinoma, Squamous Cell/pathology; DNA Damage; Exodeoxyribonucleases/genetics; Exodeoxyribonucleases/metabolism*; Female; Humans; Keratinocytes/enzymology; Keratinocytes/radiation effects; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphoproteins/genetics; Phosphoproteins/metabolism*; Skin Neoplasms/enzymology*; Skin Neoplasms/etiology; Skin Neoplasms/pathology; Ultraviolet Rays/adverse effects*;

Open Access Type

Gold

DOI

10.18632/oncotarget.4296

PubMed ID

26090614