A Study of Applicability of SNP Chips Developed for Bovine and Ovine Species to Whole-Genome Analysis of Reindeer Rangifer tarandus

Autor:in

Veronika, Kharzinova; Сермягин, Александр; Gladyr, Elena; Innokentiy, Okhlopkov; Brem, G.; Zinovieva, Natalia

Abstrakt

Two sets of commercially available single nucleotide polymorphisms (SNPs) developed for cattle BovineSNP50 BeadChip) and sheep (OvineSNP50 BeadChip) have been trialed for whole-genome analysis of 4 female samples of Rangifer tarandus inhabiting Russia. We found out that 43.0% of bovine and 47.0% of Ovine SNPs could be genotyped, while only 5.3% and 2.03% of them were respectively polymorphic. The scored and the polymorphic SNPs were identified on each bovine and each ovine chromosome, but their distribution was not unique. The maximal value of runs of homozygosity (ROH) was 30.93 Mb (for SNPs corresponding to bovine chromosome 8) and 80.32 Mb (for SNPs corresponding to ovine chromosome 7). Thus, the SNP chips developed for bovine and ovine species can be used as a powerful tool for genome analysis in reindeer R. tarandus.

Dokumententyp

Originalarbeit

DOI

10.1093/jhered/esv081

PubMed ID

MEDLINE:26447215