Envelope-modified single-cycle simian immunodeficiency virus selectively enhances antibody responses and partially protects against repeated, low-dose vaginal challenge.

Autor:in

Alpert, Michael D; Rahmberg, Andrew R; Neidermyer, William; Ng, Sharon K; Carville, Angela; Camp, Jeremy V; Wilson, Robert L; Piatak, Michael; Mansfield, Keith G; Li, Wenjun; Miller, Christopher J; Lifson, Jeffrey D; Kozlowski, Pamela A; Evans, David T;

Schlagwörter

Animals; Antibodies, Neutralizing/biosynthesis; Antibodies, Viral/biosynthesis*; Female; Genes, Viral; Immunization, Secondary; Macaca mulatta; Membrane Glycoproteins/genetics; Membrane Glycoproteins/immunology*; Retroviridae Proteins/genetics; Retroviridae Proteins/immunology*; SAIDS Vaccines/administration & dosage; SAIDS Vaccines/genetics; SAIDS Vaccines/immunology; Simian Acquired Immunodeficiency Syndrome/immunology; Simian Acquired Immunodeficiency Syndrome/prevention & control; Simian Acquired Immunodeficiency Syndrome/virology; Simian Immunodeficiency Virus/genetics; Simian Immunodeficiency Virus/immunology*; Simian Immunodeficiency Virus/pathogenicity*; Vaccines, Synthetic/administration & dosage; Vaccines, Synthetic/genetics; Vaccines, Synthetic/immunology; Vagina/immunology; Vagina/virology; Vesiculovirus/genetics; Viral Envelope Proteins/genetics; Viral Envelope Proteins/immunology*; Viral Load;

ISSN/eISSN

0022-538X -

WoS ID

WOS:000282642600029