Zeitschriftenaufsatz | 2006

Clusterin is not essential for androgen-regulated involution and regeneration of the normal mouse prostate.

Autor:in

Fink, Dieter; Fazli, Ladan; Aronow, Bruce; Gleave, Martin E; Ong, Christopher J;

Journal

Prostate

Schlagwörter

Androgens/physiology*; Animals; Apoptosis/physiology; Clusterin/genetics; Clusterin/physiology*; Male; Mice; Mice, Knockout; Mutation/genetics; Orchiectomy; Prostate/cytology; Prostate/growth & development*; Prostate/physiology; Regeneration/physiology*;

Dokumententyp

Originalarbeit

ISSN/eISSN

0270-4137 -

DOI

10.1002/pros.20461

WoS ID

WOS:000240334700011

PubMed ID

16865725

Weitere Details

Band

66

Startseite

1445

letzte Seite

1454

Nummer

13

@enInhibition of clusterin expression has been shown to enhance the sensitivity of prostate cancer cells to chemo and hormone therapy. Clusterin antisense oligonucleotides (ASOs) are currently in phase II human clinical trials for treatment of hormone refractory prostate cancer. However, the role of clusterin in androgen-regulated involution and regeneration of the normal prostate gland has not been established.

Download
RDF/XML-Format
JSON-LD-Format
Turtle-Format
N3-Format

@enInhibition of clusterin expression has been shown to enhance the sensitivity of prostate cancer cells to chemo and hormone therapy. Clusterin antisense oligonucleotides (ASOs) are currently in phase II human clinical trials for treatment of hormone refractory prostate cancer. However, the role of clusterin in androgen-regulated involution and regeneration of the normal prostate gland has not been established.

Download
RDF/XML-Format
JSON-LD-Format
Turtle-Format
N3-Format