Off-Target Inhibition of Human Dihydroorotate Dehydrogenase (hDHODH) Highlights Challenges in the Development of Fat Mass and Obesity-Associated Protein (FTO) Inhibitors.

Autor:in

Tarullo, Marco; Fernandez Rodriguez, Guillermo; Iaiza, Alessia; Venezia, Sara; Macone, Alberto; Incocciati, Alessio; Masciarelli, Silvia; Marchioni, Marcella; Giorgis, Marta; Lolli, Marco Lucio; Fornaseri, Federico; Proietti, Ludovica; Grebien, Florian; Rosignoli, Serena; Paiardini, Alessandro; Rotili, Dante; Mai, Antonello; Bochenkova, Elena; Caflisch, Amedeo; Fazi, Francesco; Fatica, Alessandro

Journal

Acs Pharmacology & Translational Science

Dokumententyp

Originalarbeit

Open Access Type

Hybrid

DOI

10.1021/acsptsci.4c00533

PubMed ID

39698280

Projekt

Age-Related Changes in Hematopoiesis; Evaluation of ABC transporters in Leukemia