Zeitschriftenaufsatz | 2013 Open Access

CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response.

Autor:in

Bancerek, Joanna; Poss, Zachary C; Steinparzer, Iris; Sedlyarov, Vitaly; Pfaffenwimmer, Thaddäus; Mikulic, Ivana; Dölken, Lars; Strobl, Birgit; Müller, Mathias; Taatjes, Dylan J; Kovarik, Pavel;

Publikationen als Autor:in / Herausgeber:in der Vetmeduni

Müller, Mathias; Strobl, Birgit

Journal

Immunity

Schlagwörter

Animals; Cyclin-Dependent Kinase 8/genetics*; Cyclin-Dependent Kinase 8/immunology; Cyclin-Dependent Kinase 8/metabolism; Fibroblasts/drug effects; Fibroblasts/metabolism; Fibroblasts/virology; Gene Expression Regulation/drug effects*; Hep G2 Cells; Humans; Interferon-gamma/immunology; Interferon-gamma/pharmacology*; Interleukin-6/immunology; Interleukin-6/pharmacology; Mice; Oligonucleotide Array Sequence Analysis; Phosphorylation; Promoter Regions, Genetic; RNA Polymerase II/genetics; RNA Polymerase II/immunology; STAT1 Transcription Factor/genetics*; STAT1 Transcription Factor/immunology; STAT1 Transcription Factor/metabolism; STAT3 Transcription Factor/genetics; STAT3 Transcription Factor/immunology; STAT5 Transcription Factor/genetics; STAT5 Transcription Factor/immunology; Signal Transduction/drug effects; Transcription, Genetic/drug effects; Vesiculovirus/physiology;

Dokumententyp

Originalarbeit

ISSN/eISSN

1074-7613 -

DOI

10.1016/j.immuni.2012.10.017

WoS ID

WOS:000330940800008

PubMed ID

23352233